High-Stakes Decisions Deserve Clinical Truth.

From market sizing to drug uptake forecasts to RWD due diligence, the signals that matter live in the clinical record.

Lighten delivers complete clinical intelligence to ground your decisions in what's actually happening to patients.

Core Capabilities

The Foundation of Informed Investment Decisions.

the True Addressable Patient Population
Market sizing that holds up to diligence.

In-licensing, out-licensing, and biotech investment decisions all hinge on market sizing. Claims-based sizing mixes true patients with false positives and misses the patients who never generated a billable encounter.

Lighten establishes the clinical ground truth from EHRs and scales it across claims, so your market model reflects real patients, not billing code proxies.

Patient Journey Intelligence
Market intelligence & demand forecasting

Drug uptake, switch dynamics, and competitive share shifts are rooted in clinical decisions. Lighten delivers clinically validated patient journeys, ongoingly updated.

Know what's in the data before you invest
RWD Due Diligence

Lighten provides independent, clinically validated assessments of RWD assets — evaluating coherence, extractability, and fitness-for-use against targeted use cases.

Case studies

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The Same Patients, Completely Different Answers

How integrating EHR with claims changes every conclusion, from market sizing to disease burden.

Case Study

New Frontier in Patient Finding: Scaling EHR Signals to Claims

6x more confirmed patients. 37% higher precision vs. using standard claims criteria.

Case Study

Lighten's Four Pillar Quality Framework

Beyond any single metric, discover how to achieve clinically validated quality.

White Paper